Search on: SKP CULLIN F-BOX PROTEIN LIGASES 
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Descriptor English:   SKP Cullin F-Box Protein Ligases 
Descriptor Spanish:   Proteínas Ligasas SKP Cullina F-box 
Descriptor Portuguese:   Proteínas Ligases SKP Culina F-Box 
Synonyms English:   SCF Ubiquitin Ligase  
Tree Number:   D08.811.464.938.750.750
Definition English:   A subset of ubiquitin protein ligases that are formed by the association of a SKP DOMAIN PROTEIN, a CULLIN DOMAIN PROTEIN and a F-BOX DOMAIN PROTEIN. 
See Related English:   Cullin Proteins
F-Box Proteins
S-Phase Kinase-Associated Proteins
 
History Note English:   2004; use SKP CULLIN F-BOX LIGASES (NM) 1999-2003 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   38184 
Unique Identifier:   D044843 

Occurrence in VHL:
 

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